A patient has been placed on tacrolimus, and the route will be changed from IV to oral prior to discharge home from the hospital. How will this change in administration route affect the patient's plan of care?
A) The patient's dose of tacrolimus will have to be increased.
B) The patient will receive the drug QID rather than BID
C) The patient will have to be monitored more closely for adverse effects.
D) The patient will have to take tacrolimus concurrently with an antiemetic.
A
Feedback:
Tacrolimus, like cyclosporine, is not well absorbed orally, so it is necessary to give higher oral doses than IV doses to obtain similar blood levels. Increased frequency is not necessarily required. Concurrent dosing with an antiemetic is not required. Regardless of the route by which the drug is provided, the patient needs to be closely monitored for adverse effects.
You might also like to view...
Clients are taught to use a clean technique for irrigating, changing, or inserting catheters at home
Indicate whether the statement is true or false
The nurse is preparing an analgesic infusion for a cancer patient who is in pain and is nearing the end of life. What should the nurse do to ensure this patient's comfort?
1. Titrate the medication to help with pain relief and not hasten the dying process. 2. Use meperidine in the infusion. 3. Limit the amount of medication infused. 4. Contact the pharmacy for the correct dose to provide the patient.
Name four ways haemostasis occurs or is achieved in surgery, and give examples of what would be used to achieve this
John North, 53, has a history of type I diabetes mellitus, cigarette smoking (40 pack years), coronary artery disease (CAD) and peripheral vascular disease (PVD). Six weeks ago, he developed a wound on his left heel that measured 4 cm by 2 cm. Despite IV antibiotics and chemical debridement, the wound developed a gangrene infection. He is scheduled for a below knee amputation (BKA) of the left lower extremity tomorrow at 10 am. His meds include daily insulin, aspirin 325 mg/day and Pletal (cilostazol) 100 mg b.i.d. He has an advanced directive and no known drug allergies (NKDA). What will be an ideal response?
A nurse received a report from the gastrointestinal department and is waiting to admit a client with hypocalcemia due to malabsorption who is being treated for a broken wrist. Which calcium-related food does the nurse suggest? Select all that apply.
A) Broccoli B) Kale C) Salmon D) Soybeans E) Coffee