Why are older adults more prone to adverse drug reactions and interactions than younger adults?
1. Presence of fewer chronic disease states
2. More predictable pharmacokinetics and pharmacodynamics
3. Use of fewer chronic medications
4. Physiologic changes in body composition
Correct Answer: 4
Rationale 1: Older clients tend to have more chronic disease states, not fewer.
Rationale 2: Pharmacokinetics are less predictable in older clients, not more.
Rationale 3: Older clients tend to use more chronic medications, not fewer.
Rationale 4: Physiologic changes in body composition can affect drug pharmacokinetics, increasing the risk of adverse drug reactions and interactions.
Global Rationale: Physiologic changes in body composition can affect drug pharmacokinetics, increasing the risk of adverse drug reactions and interactions. Older clients tend to have more chronic disease states, not fewer. Pharmacokinetics are less predictable in older clients, not more. Older clients tend to use more chronic medications, not fewer.
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