Adaptive immunity is ________, while innate immunity is ________
a. specific / non-specific
b. non-specific / specific
c. slower / faster
d. born / developed
Answer: A
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Tacrolimus (FK-506) is a drug that inhibits an enzyme called calcineurin. Calcineurin is a protein phosphatase. This is an enzyme that dephosphorylates (removes phosphate groups) from proteins. When added to cells, tacrolimus can inhibit the dephosphorylation of a protein called NFAT, but it cannot prevent the dephosphorylation of a protein called CDK1. What is the most likely explanation for this finding?
A. Calcineurin requires an additional cofactor to dephosphorylate NFAT B. NFAT is a substrate of calcineurin, but CDK1 is not C. Tacrolimus is a competitive inhibitor of calcineurin for NFAT and CDK11 D. Tacrolimus changes the optimum pH for calcineurin Clarify Question What is the key concept addressed by the question? What type of thinking is required? Gather Content What do you already know about phosphates and enzymestructure? What other information is related to the question? Choose Answer Do you have all necessary information to analyze how tacrolimus works on NFAT and CDK1? Reflect on Process Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
Earth's early atmosphere contained (select all that apply):
A. methane. B. water. C. nitrogen. D. hydrogen. E. organic molecules.
Which of the following represents a sequence located upstream, downstream, within the coding region, or several thousand base pairs away from a gene that increases transcription?
a. promoter b. terminator c. repressor d. enhancer
In chickens, there is a mutant gene called "frizzle" that results in weak, stringy, and easily broken feathers. When a frightfully frizzled fowl is bred to a normal chicken, the offspring are all mildly frizzled
If one breeds two mildly frizzled chickens to each other, the offspring have the phenotypic ratio of 1 normal: 2 mildly frizzled: 1 frightfully frizzled. What is the mode of inheritance of "frizzle"?