A male patient whose father died of prostate cancer is concerned about his risk of developing the disease. He states he has heard that prostate cancer has a genetic link. What response is most accurate about prostate cancer?
A) "A number of studies have identified an association of BRCA-2 mutation with an increased risk of prostate cancer."
B) "HNPCC is a mutation of two genes that causes prostate cancer in men and is autosomal dominant."
C) "The mutation of the APC gene will result in the development of prostate cancer in middle-age men."
D) "BRCA-1 is a mutant allele associated with autosomal-dominant predisposition to prostate cancer."
Ans: A
Feedback: A number of studies have identified an association of BRCA-2 mutation with an increased risk of prostate cancer. BRCA-1 is a mutant allele which is an autosomal dominantly and predisposes women to breast cancer. HPNCC has two forms that are associated with colon cancer development. The APC gene causes the formation of benign tumors.
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