A patient with cancer is taking rasburicase [Elitek] to treat hyperuricemia and develops neutropenia with fever and respiratory distress on the fourth day of treatment. The nurse caring for this patient will expect to:
a. administer allopurinol instead of rasburi-case.
b. continue giving the drug and monitor the patient's symptoms closely.
c. tell the patient that this drug should never be used again.
d. tell the patient that these symptoms indi-cate severe sepsis.
B
Rasburicase is used for management of hyperuricemia in patients undergoing treatment with chemotherapy for leukemias, lymphomas, and solid tumors. Fever and respiratory distress may occur; patients should be monitored closely. These symptoms do not warrant stopping the drug, and they do not indicate severe sepsis.
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