A client prescribed doxazosin for hypertension asks the nurse how the medication works. Which of the following should the nurse respond to the client?
1. "It works by causing the kidneys to excrete more urine.".
2. "It works by making the blood vessels expand.".
3. "It works by making the heart work more efficiently.".
4. "It works by decreasing the release of stress hormones.".
2. "It works by making the blood vessels expand.".
Rationale:
Doxazosin is selective for blocking alpha1-receptors in vascular smooth muscle, which results in dilation of arteries and veins. Excreting more urine is an effect of diuretic medications. Increasing the efficiency of the heart is not an effect of doxazosin. Decreasing the release of stress hormones is not an effect of doxazosin.
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