What is the priority reason for the nurse to consider questioning an order for tetracycline in a child younger than 8 years of age?
A) Children younger than 8 years of age cannot take tetracyclines.
B) Weight-bearing joints have been impaired in young animals given the drugs.
C) Tetracyclines can damage developing teeth and bone in children younger than 8 years of age.
D) Liver and kidney function may be damaged when it is given to children under 8 years of age.
C
Feedback:
Use tetracyclines with caution in children younger than 8 years of age because they can potentially damage developing bones and teeth. Although the drug does not cause damage to liver and kidneys, it may be contraindicated in patients with hepatic or renal dysfunction because it is concentrated in the bile and excreted in the urine. Fluoroquinolones, not tetracyclines, are generally contraindicated for use in children (i.e., those younger than 18 years of age) because weight-bearing joints have been impaired in young animals given the drugs. Clindamycin (Dalacin C) warrants monitoring hepatic and renal function when it is given to neonates and infants. Trimethoprim–sulfamethoxazole (Nu-Cotrimox) is used in children, although children younger than 2 months of age have not been evaluated. Children under 8 years of age can take tetracycline, but it should be used with caution.
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