A client is taking spironolactone (Aldactone) but continues to have peripheral edema. Which question by the nurse is the most appropriate?
1. Are you taking potassium supplements?
2. Are you taking corticosteroids?
3. Are you taking digoxin (Lanoxin)?
4. Are you taking aspirin (ASA)?
4
Rationale 1: Hyperkalemia may occur if the client is also taking a potassium supplement but not peripheral edema.
Rationale 2: The effects of corticosteroids are increased with thiazides.
Rationale 3: Spironolactone decreases the effects of digoxin, which would not cause peripheral edema.
Rationale 4: Aspirin and other salicylates can decrease the diuretic effect of spironolactone.
Global Rationale: Aspirin and other salicylates can decrease the diuretic effect of spironolactone. Hyperkalemia may occur if the client is also taking a potassium supplement. The effects of corticosteroids are increased with thiazides. Spironolactone decreases the effects of digoxin, which would not cause peripheral edema.
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