A 77-year-old female diagnosed with chronic obstructive pulmonary disease (COPD) is experiencing impaired gas exchange and CO2 retention, despite a rapid respiratory rate
Which of the following pathophysiological principles would her health care team expect if her compensatory mechanisms are working?
A)
Arterial blood gas sampling indicates a pH in the range of 7.45 to 7.55.
B)
Her kidneys are likely to reabsorb H+ and secrete HCO3-
C)
Her body will produce excess metabolic CO2.
D)
Her kidneys will adapt with an increase in plasma HCO3- and her pH will decrease.
Ans:
D
Feedback:
Respiratory acidosis is accompanied by renal adaptation with a more marked increase in plasma HCO3- and a lesser decrease in pH. Her pH is likely below 7.35, and the likely renal response involves the reabsorption of HCO3- and secretion of H+. Excess CO2 production is not a common manifestation of obstructive lung disease.
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