A client who has been taking clozapine for 6 weeks visits the clinic complaining of fever, sore throat, and mouth sores. The nurse notifies the client's physician because the nurse suspects which of the following?
A) Severe anemia
B) Neuroleptic malignant syndrome
C) Encephalitis
D) Agranulocytosis
Ans: D
High fever, sore throat, and mouth sores are indicative of infection secondary to agranulocytosis, which has been associated with clozapine. The medication can suppress the bone marrow and cause a significant decrease in white blood cells. The client's signs and symptoms do not suggest anemia, neuroleptic malignant syndrome, or encephalitis.
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