A child has been admitted with assessment findings suggestive of hemophilia. Which laboratory test would the nurse evaluate as supporting that diagnosis?

1. Decreased red blood cell count on CBC
2. Prolonged partial thromboplastin time (aPTT)
3. Decreased factor VI
4. A positive d-dimer


2
Rationale 1: Any person who is bleeding would have a decreased red blood cell count; this is not specific to hemophilia.
Rationale 2: Because hemophilia is a disorder of the intrinsic pathway, the patient typically will have a prolonged aPTT.
Rationale 3: The factors that are insufficient in hemophilia are factors VIII and IX.
Rationale 4: The d-dimer test indicates excessive fibrinolysis, the end point of excessive activation of the clotting pathways. This is not part of the pathophysiology of hemophilia.

Nursing

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