The intrinsic coagulation pathway is activated when
a. local blood vessels constrict at the injury site.
b. damaged endothelium comes into contact with circulating blood.
c. tissue factor is released by injured cells.
d. fibrinogen is converted to fibrin.
B
The extrinsic pathway begins when vascular injury causes the release of tissue factor. The intrinsic pathway begins when damaged endothelium comes into contact with circulating blood. The two pathways converge when fibrinogen and prothrombin are converted to their active forms and a clot is established.
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