A middle-aged woman has acromegaly as a result of a pituitary adenoma that was found and removed when she was a teenager
The physician is suspecting that the tumor has returned and has ordered a diagnostic work-up. A glucose load is ordered. If the tumor has returned, the nurse would expect which of the following results?
A)
The glucoses load will suppress GH level.
B)
The growth hormone level will not be suppressed following glucose load.
C)
The glucose load will raise her serum glucose level to the point of requiring insulin.
D)
There will be no change in the serum growth hormone level following the glucose load.
Ans:
B
Feedback:
When a GH-secreting tumor is suspected, the GH response to a glucose load is measured as part of the diagnostic workup. Normally, a glucose load would suppress GH levels. However, in adults with GH-secreting tumors (acromegaly), GH levels are not suppressed (and paradoxically increase in 50% of cases) to a glucose load.
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