The hospitalized patient is receiving spironolactone (Aldactone). A consulting physician sees the patient and orders lisinopril (Prinivil). What will be the primary assessment by the nurse?
1. Decreased effect of spironolactone (Aldactone)
2. Hypokalemia
3. Hyperkalemia
4. Decreased effect of lisinopril (Prinivil)
Correct Answer: 3
Rationale: Concurrent use of spironolactone (Aldactone) and ACE inhibitors such as lisinopril (Prinivil), may predispose the patient to hyperkalemia. The patient will be at risk for hyperkalemia, not hypokalemia. Lisinopril (Prinivil) does not decrease the effect of spironolactone (Aldactone). Spironolactone (Aldactone) does not decrease the effect of spironolactone (Aldactone).
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