1. Both alcohol and sedatives affect GABA.
2. With serious, dangerous drugs, such as methamphetamine or heroin, a single use is sufficient for a diagnosis of a substance use disorder.
3. Adolescents with substance use disorders are more likely to show comorbid mood and anxiety disorders than adults are.
4. There is a higher rate of suicide attempts among adolescents with substance use Ddisorder than among adolescents without substance use disorder.